Dr. Gaudet leads a team of expert biologists who integrate data from other databases, published studies, and data submissions from researchers. Users of neXtProt include researchers, members of the Human Proteomics Organisation (HUPO), as well as pharmaceutical companies.Pascale Gaudet obtained her PhD degree from Concordia University in Montreal, Canada, in 2001, and started working in the field of biocuration shortly after. In October 2010, she undertook the position of Scientific Manager at the neXtProt database in the CALIPHO group of the Swiss Institute of Bioinformatics (SIB).
Dr Gaudet's first position as a biocurator was with the Model Organism Database dictyBase at Northwestern University, in Chicago, where she analyzed and annotated the genome of the unicellular eukaryote Dictyostelium discoideum. One of the aspects of annotation was to assign Gene Ontology categories to gene products. In 2006, the Gene Ontology Consortium intiated a project called 'Reference Genome', a large scale effort to annotate a number of representative ("reference") species with Gene Ontology terms from the experimental literature, and propagate those annotations to evolutionary related proteins. Dr Gaudet was made manager, and has been overseeing the project ever since.
Dr Gaudet is one of the founding members and the Chairperson of the International Society for Biocuration, a non-profit organization aiming to facilitate interactions between biologists and computer scientists developing biological databases and related resources. The larger goal is to improve the overall quality of the resources, ensure their stability, and encourage the continued recruitment of high quality scientists to the field. One of the projects lead by the ISB is BioDBCore, a uniform description of the core attributes of biological databases. BioDBcore aims to improve interoperability between resources, provide guidance for users, and ultimately maximize the collective impact of these resources.